Gaining Insights into the Small Molecule Targeting of the G-Quadruplex in the c-MYC Promoter Using NMR and an Allele-Specific Transcriptional Assay, by Christine E. Kaiser, Vijay Gokhale, Danzhou Yang and Laurence H. Hurley.- Higher-Order Quadruplex Structures, by Luigi Petraccone.- Investigation of Quadruplex Structure Under Physiological Conditions Using In-Cell NMR, by Robert Hänsel, Silv…
Assisting Oxidative Protein Folding: How Do Protein Disulphide-Isomerases Couple Conformational and Chemical Processes in Protein Folding?, by A. Katrine Wallis and Robert B. Freedman Peptide Bond cis/trans Isomerases: A Biocatalysis Perspective of Conformational Dynamics in Proteins, by Cordelia Schiene-Fischer, Tobias Aumüller and Gunter Fischer Small Heat-Shock Proteins: Paramedics of the…
Despite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory…
The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecul…
This is the first comprehensive overview of this topic. It serves as a single source for information about the properties, preparation, and uses of all relevant primary explosives. The first chapter provides background such as the basics of initiation and differences between requirements on primary explosives used in detonators and igniters. The authors then clarify the influence of physical ch…
This reference work provides a wealth of information regarding medicinal plants and phytochemicals. It is addressed both to researchers and teachers. The handbook describes phytochemicals, which, by the strictest definition, are chemicals that are produced by plants. During the last decades, more and more groups became actively involved in exploring plants for useful metabolites that lead to…
The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehens…
Chiral Derivatizing Agents, Macrocycles, Metal Complexes and Liquid Crystals for Enantiomer Differentiation in NMR Spectroscopy: Thomas J. Wenzel. Chiral NMR Solvating Additives for Differentiation of Enantiomers: Gloria Uccello-Barretta and Federica Balzano. Chiral Sensor Devices for Differentiation of Enantiomers: Kyriaki Manoli, Maria Magliulo and Luisa Torsi. Enantiopure supramolecular cage…
Emphasis is on a broad description of the general methods and processes for the synthesis, modification and characterization of macromolecules. These more fundamental chapters will be supplemented by selected and detailed experiments. In addition to the preparative aspects, the book also gives the reader an impression on the relation of chemical constitution and morphology of Polymers to their …