Structural and functional characterization of the immunoproteasome

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Structural and functional characterization of the immunoproteasome

Huber, Eva Maria - Nama Orang;

In this acclaimed thesis, Eva Maria Huber reveals ground-breaking results by elucidating the crystal structure of the murine immunoproteasome in complex with a selective inhibitor. Huber does this by performing multidisciplinary methodologies including X-ray crystallography, fluorescence spectroscopy and mutagenesis experiments. Her exceptional results explore the immunoproteasome complex structures and are of outstanding importance for future scientific research especially in the pharmaceutical industry. These results will enable the functional analysis of individual proteasome subunits and support the development of novel drugs for autoimmune diseases such as multiple sclerosis or rheumatoid arthritis.

Ketersediaan

Perpustakaan Pusat E222

E222

Tersedia

Informasi Detail

Judul Seri: Springer Theses
No. Panggil: E222
Penerbit: Cham : Springer., 2013
Deskripsi Fisik: XIX, 82 lembar : il. warna
Bahasa: English
ISBN/ISSN: 9783319015569
Klasifikasi: NONE
Tipe Isi: text
Tipe Media: computer
Tipe Pembawa: online resource
Edisi: -
Subjek: Kimia Analitis
Protein
Info Detail Spesifik: -
Pernyataan Tanggungjawab: Eva Maria Huber

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Structural and functional characterization of the immunoproteasome
https://doi.org/10.1007/978-3-319-01556-9

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